Arginine alpha ketoglutarate or AAKG is a chemical compound made from combining the salt of arginine and alpha ketoglutaric acid, two important chemical compounds necessary to produce the compound nitric oxide. It is a well known compound because it is widely sold in the market as a dietary supplement that builds muscle mass.

Arginine alpha ketoglutarate supplement is sold in the market for body building purposes. It is administered to patients who have just undergone surgery to promote hormone production and release of insulin for the purpose of healing wounds in a speedy manner. AAKG has the ability to speed up recovery after a serious injury and is also used to treat severe burns and other traumatic damage to the body.

Previous laboratory experiments show that AAKG supplementation dramatically increased collagen production deposited in a wound as evidenced by the presence of the substance hydroxyproline in the wound.

Wound healing is greatly enhanced by the arginine content in AAKG and increases the producttion of hydroxyproline levels in the wound area when tested among the diabetic laboratory animals. AAKG supplementation also significantly increased the amount of fluid nitrate and nitrite levels in the site of the injury.

It is also believed that this substance can reduce blood pressure. Nitric oxide, which is produced from arginine has the ability to dilate blood vessels resulting to the relaxation of muscles in the arteries, arterioles and veins. It is believed that the nitric oxide content in AAKG is responsible for the production of muscle proteins in the body and further enhances muscular strength and endurance, however further research is needed to confirm this claim. It ensures a regular supply of healthy blood to the muscles and other parts of the body.

During great stress and traumatic injury, the glutamine and arginine content found in our skeletal muscles are significantly increased with arginine alpha ketoglutarate supplementation.

It is also believed to increase the amount of growth hormones especially in children where a study showed that the AAKG supplementation indeed increased the levels of growth hormones and amino acids in the body.

The benefits from arginine alpha ketoglutarate are almost the same as those derived from arginine. It is used to speed up the healing of wounds especially after surgery and repair of cells and tissues of the body after severe wounds and body injury. It also treats headaches caused by severe migraine and treats impotence among the male population.